Category Archives: brain

“Chemical chaperone” improves Alzheimer’s signs in early & late disease

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Treatment with a supplementary 'chemical chaperone' has been shown to reduce protein plaques and improve cognitive performance in Alzheimer's disease

A new study has found that treatment with a ‘chemical chaperone’ assists in reducing the accumulation of protein plaques and restores cognitive functioning in mouse models of Alzheimer’s disease. The findings could lead to novel treatments to help treat this debilitating disease.

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Single-dose drug to quash anxiety passes another trial milestone

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An effective single-dose, long-term treatment for anxiety could be within reach, with the phase 2b clinical trial of MM-120 reported to have passed the stage with flying colors. The makers, MindMed, now plan to hold an end-of-phase meeting with the US … Continue reading Single-dose drug to quash anxiety passes another trial milestone→

Cyborg computer with living brain organoid aces machine learning tests

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Scientists have grown a tiny brain-like organoid out of human stem cells, hooked it up to a computer, and demonstrated its potential as a kind of organic machine learning chip, showing it can quickly pick up speech recognition and math predictions.Cont… Continue reading Cyborg computer with living brain organoid aces machine learning tests→

Purr-fect storm: House cats linked to 2x risk of schizophrenia

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A comprehensive meta-analysis of 17 studies across 11 countries over 44 years has resoundingly supported the growing evidence that sharing your childhood home with a cat is connected to a significant increase in risk of developing schizophrenia.Continu… Continue reading Purr-fect storm: House cats linked to 2x risk of schizophrenia→

Rogue protein linked to early-onset dementia identified

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A visualization of the structure of TAF15 amyloid filaments (in yellow), as detected by cryo-EM in the brains of four dementia patients

Scientists have identified odd clusters of a specific protein in the brains of people with early-onset dementia, pointing to a potential cause, a diagnostic tool and, ultimately, a therapy target for a disease that’s been largely a mystery to researchers.

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Microbubble bots guided through complex brain vessels using ultrasound

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Researchers have developed a bubble microrobot capable of being guided around the tiny complex blood vessels of the brain using ultrasound. Successfully tested in mice, the ‘microvehicle’ holds potential as a means of precisely delivering drugs to trea… Continue reading Microbubble bots guided through complex brain vessels using ultrasound→

Mouse passes mirror test, joining elite club of ‘self-aware’ animals

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Joining the likes of killer whales (Orcinus orca) and bottlenose dolphins (Tursiops truncatus), plus a number of primates, a common dark-furred mouse has passed what’s known as the mirror test, backed up by gene mapping, that suggests it may possess we… Continue reading Mouse passes mirror test, joining elite club of ‘self-aware’ animals→

Twice-daily brain zaps may boost ‘rewiring’ & functioning in Alzheimer’s

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A study found that twice-daily non-invasive electrical stimulation improved brain functioning in patients with Alzheimer's disease

Research has found that non-invasively applying a mild electrical current to the brain twice a day for six weeks improved cognitive functioning and plasticity, the ability of the brain to ‘rewire’ itself, in patients with Alzheimer’s disease. The treatment may be an effective way of reducing – or even reversing – the effects of the condition.

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Regular ketamine use found to restructure the brain’s dopamine system

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Researchers have mapped the whole brain of mice, revealing how regular ketamine use produces divergent changes in specific areas of the brain responsible for producing the ‘feel-good’ neurotransmitter, dopamine. The discovery could have significant imp… Continue reading Regular ketamine use found to restructure the brain’s dopamine system→