Heat shock proteins offer clues to reversing dementia in stressed cells

A specific type of heat shock protein was found to reverse the protein misfolding associated with several neurodegenerative diseases

Researchers investigating the effects of stress on accumulations of toxic brain proteins linked with dementia have discovered a surprisingly counter-intuitive mechanism. A specific cellular stress response involving heat shock proteins has been found to reverse the build-up of these toxic proteins and future research will now look for a way to therapeutically trigger this mechanism.

Continue Reading

Category: Science

Tags: , , , , , ,

Continue reading Heat shock proteins offer clues to reversing dementia in stressed cells

Stroke severity linked to certain strains of gut bacteria

Researchers have homed in on several strains of gut bacteria that are associated with the severity of a common form of stroke. The findings build on a growing body of research suggesting future therapies targeting the gut microbiome could reduce a pers… Continue reading Stroke severity linked to certain strains of gut bacteria

Cognitive impact of severe COVID equal to 20 years of brain aging

A new study has presented the most rigorous investigation to date into the long-term cognitive impacts of severe COVID-19. The research, led by scientists from Imperial College London and the University of Cambridge, found persistent cognitive deficits… Continue reading Cognitive impact of severe COVID equal to 20 years of brain aging

“Reset button” for cells in the brain hints at new treatments for concussion

The way the brain responds to traumatic injuries is a matter of intense interest to medical scientists investigating concussion and its significant health impacts. Through experiments on mice in which a key set of immune cells were essentially reset af… Continue reading “Reset button” for cells in the brain hints at new treatments for concussion

Trial finds insulin nasal spray may slow age-related cognitive decline

The results of a small Phase 2 clinical trial offers promising signs that daily doses of an insulin nasal spray could be used to slow age-related cognitive decline. The trial found the treatment to be effective in elderly subjects both with and without… Continue reading Trial finds insulin nasal spray may slow age-related cognitive decline

Study suggests blind people excel at memorizing spoken information

There’s a longstanding belief that when someone loses one ability, another improves correspondingly. New research bears this out – in one scenario, at least – as it indicates that blind people remember spoken information better than their sighted count… Continue reading Study suggests blind people excel at memorizing spoken information

Study finds seven hours of sleep to be optimal from middle-age onwards

A new study suggests that seven hours of sleep per night is best for brain health in middle and old age

We know sleep to be an essential ingredient for a healthy brain, but scientists continue to explore what a good night’s rest looks like at different stages of life, and how it can impact on our vulnerability to cognitive decline. A wide-ranging new study involving almost half a million subjects has provided compelling new insights, suggesting seven hours of sleep per night to be best for brain health during middle and old age.

Continue Reading

Category: Health & Wellbeing, Lifestyle

Tags: , , ,

Continue reading Study finds seven hours of sleep to be optimal from middle-age onwards

Brain chemical linked to kindness and generosity in old age

A fascinating new study has suggested a link between increased generosity in older age and levels of a neurochemical called oxytocin. The research found older people with higher levels of oxytocin were more likely to donate money to charity and be sati… Continue reading Brain chemical linked to kindness and generosity in old age

New study may explain why apathy is the first symptom of Alzheimer’s

New research hypothesizes degeneration in a brain region called the nucleus accumbens could trigger apathy, the earliest psychiatric sign of Alzheimer's disease

Compelling new research from the Indiana University School of Medicine has homed in on a degenerative mechanism that could explain why symptoms such as apathy are the first signs of Alzheimer’s disease. The findings suggest disrupting this process could slow the progression of Alzheimer’s-related dementia.

Continue Reading

Category: Science

Tags: , , , , ,

Continue reading New study may explain why apathy is the first symptom of Alzheimer’s

Portable MRI can accurately detect most common form of stroke

New research has found the world’s first portable MRI machine can accurately detect ischemic strokes. The machine was cleared for use by the US Food & Drug Administration (FDA) in 2020 and researchers are increasingly demonstrating it to be as effectiv… Continue reading Portable MRI can accurately detect most common form of stroke