RNA therapy an effective alternative to lifelong, painful eye injections

An RNA-editing gene therapy has been developed that switches off the key driver of common eye conditions affecting diabetics and the elderly. The researchers behind the innovative treatment say that it’s an alternative to the current treatment: regular… Continue reading RNA therapy an effective alternative to lifelong, painful eye injections

Magnets used to turn specific brain circuits off and on at will

Researchers have developed a gene therapy technology that uses magnetic fields to switch groups of neurons on and off, controlling brain circuits affected by Parkinson’s disease. In addition to Parkinson’s, the tech could be used to treat conditions as… Continue reading Magnets used to turn specific brain circuits off and on at will

Potential Cure For All of England’s Beta Thalassemia Patients Within Reach

A giemsa stained blood smear from a person with beta thalassemia (Credit: Dr Graham Beards, Wikimedia Commons)

Beta thalassemia and sickle cell are two red blood cell disorders which both come with massive health implications and shortened lifespans, but at least for UK-based patients the former may …read more Continue reading Potential Cure For All of England’s Beta Thalassemia Patients Within Reach

Potential Cure For All of England’s Beta Thalassemia Patients Within Reach

A giemsa stained blood smear from a person with beta thalassemia (Credit: Dr Graham Beards, Wikimedia Commons)

Beta thalassemia and sickle cell are two red blood cell disorders which both come with massive health implications and shortened lifespans, but at least for UK-based patients the former may …read more Continue reading Potential Cure For All of England’s Beta Thalassemia Patients Within Reach

Potential Cure For All of England’s Beta Thalassemia Patients Within Reach

A giemsa stained blood smear from a person with beta thalassemia (Credit: Dr Graham Beards, Wikimedia Commons)

Beta thalassemia and sickle cell are two red blood cell disorders which both come with massive health implications and shortened lifespans, but at least for UK-based patients the former may …read more Continue reading Potential Cure For All of England’s Beta Thalassemia Patients Within Reach

Muscular dystrophy-reversing gene therapy: Human trials in 2 years

A new gene therapy for Duchenne muscular dystrophy (DMD) has shown promise in not only slowing the progression of the disease but potentially even reversing the muscle damage, with human trials set to begin within two years.Continue ReadingCategory: Me… Continue reading Muscular dystrophy-reversing gene therapy: Human trials in 2 years

Engineered mRNA turns your body into a drug-making biofactory

Messenger RNA (mRNA) contains the instructions that direct a cell to make a specific protein using its built-in machinery. Many will be aware of mRNA because of its association with the COVID-19 vaccine. But mRNA has potential uses far beyond that, inc… Continue reading Engineered mRNA turns your body into a drug-making biofactory

Gene therapy repairs spinal discs to relieve back pain

It feels like back pain comes for many of us at some point in our lives, and it’s tricky to treat. A new gene therapy, which repairs damaged discs and reduces pain, has shown promise in mouse tests.Continue ReadingCategory: Medical, ScienceTags: Back P… Continue reading Gene therapy repairs spinal discs to relieve back pain

CRISPR restores some vision to blind patients in clinical trial

CRISPR gene-editing has improved the vision of patients with an inherited form of blindness, according to results of a Phase 1/2 clinical trial. The results not only give new hope to patients with the condition, but show that CRISPR could be put to use… Continue reading CRISPR restores some vision to blind patients in clinical trial

Cow’s milk particles unlock one of medicine’s most challenging puzzles

A particle in cow's milk enables RNA therapy to be given orally

One of the biggest challenges researchers face is making injectable medicines into versions that can be taken orally. Oral medications usually fail because they can’t withstand the harsh environment of the gut, which leads to poor bioavailability – a drug’s ability to be absorbed and exert a therapeutic effect on the body.

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Continue reading Cow’s milk particles unlock one of medicine’s most challenging puzzles