Protein identified as key link between appetite suppression and obesity

Among the many interesting scientific advances we are seeing around obesity and how it might best be tackled, one hormone central to the regulation of appetite routinely rears its head. Called leptin, a new study has revealed some of the molecular mach… Continue reading Protein identified as key link between appetite suppression and obesity

Failed Alzheimer’s drug finds new life as anti-obesity pill

Since the drug already has an established safety profile the researchers suggest human clinical trials for obesity could swiftly commence

An experimental drug originally designed to treat Alzheimer’s has been found to reduce obesity and improve heart function in mice. The drug was previously found to be ineffective at treating dementia, but the researchers suggest it could be useful in stimulating fat metabolism.

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Continue reading Failed Alzheimer’s drug finds new life as anti-obesity pill

Gene discoveries present new drug targets for treating obesity

In the ongoing search for new treatments for obesity and its related conditions, scientists are turning considerable attention to the role our genes might play. The hope is that drugs could one day be developed to switch key genes on or off in at-risk … Continue reading Gene discoveries present new drug targets for treating obesity

Study pinpoints “interpreter” cells that trigger burning of deep fat

The human body contains a number of different types of fat, and one with particularly insidious effects is visceral fat, which can be found deep inside the abdominal cavity. These deep-lying fat stores wrap around the organs and are linked to a range o… Continue reading Study pinpoints “interpreter” cells that trigger burning of deep fat

Researchers discover how fructose enhances fat absorption in the gut

A new preclinical study published in the journal Nature is demonstrating how fructose can alter cells in the small intestine, subsequently enhancing nutrient absorption and promoting weight gain. The research indicates excessive fructose consumption, s… Continue reading Researchers discover how fructose enhances fat absorption in the gut

Fat cell distress signal could help unlock the “obesity paradox”

Obesity is associated with a whole range of health problems, but in some specific cases, it appears to be protective in the short term against cardiovascular disease. This “obesity paradox” remains mysterious, but now researchers may have uncovered one… Continue reading Fat cell distress signal could help unlock the “obesity paradox”

How gut bacteria pave the road from high-fat diet to heart disease

Robust new research, published in the journal Science, has revealed a microbial mechanism connecting obesity with heart disease. The study describes how a high-fat diet damages intestinal cells, leading to an imbalance of bad bacteria that produce meta… Continue reading How gut bacteria pave the road from high-fat diet to heart disease

Immune signaling molecule boosts fat-burning to prevent obesity

There are different types of fat in the body that perform very different roles, and by promoting the production of one over the other scientists hope to develop new forms of treatment for conditions like obesity and diabetes. Scientists in China have i… Continue reading Immune signaling molecule boosts fat-burning to prevent obesity

Mice sweating fat raises prospect of unusual anti-obesity therapy

Scientists looking for novel ways to treat type 2 diabetes have stumbled across a mechanism by which the immune system can trigger the secretion of fat cells through the skin. The mechanism may translate from animal studies into humans, but turning it … Continue reading Mice sweating fat raises prospect of unusual anti-obesity therapy

AI tool can measure fat around the heart and calculate one’s diabetes risk

Accumulation of fat specifically around the heart has long been linked to cardiovascular and metabolic disease but until now there hasn’t been a simple way to measure this. A new artificial intelligence tool has been developed that can quantify these f… Continue reading AI tool can measure fat around the heart and calculate one’s diabetes risk