Tag Archives: Fat cells

New hypothesis argues leaky blood-brain barrier triggers Alzheimer’s

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A new hypothesis proposes fatty molecules in the blood stream invade the brain through a leaky blood brain barrier and this processes triggers Alzheimer's disease

A new article in the Journal of Alzheimer’s Disease Reports has proposed a novel hypothesis for the cause of Alzheimer’s disease. The article argues Alzheimer’s is caused by a damaged blood-brain barrier allowing fatty molecules known as lipids to invade the brain and trigger a cascade of events that result in neurodegeneration and cognitive decline.

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Repairing cell structures altered by obesity restores metabolic function

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Improving our understanding of the impact obesity has on individual cells could go a long way to preventing some of its deleterious downstream effects, such as diabetes and cardiovascular disease. Harvard scientists studying the molecular structure of … Continue reading Repairing cell structures altered by obesity restores metabolic function→

Tweaks to immune checkpoint proteins apply brakes to obesity

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Research continues to uncover the role that inflammation plays in obesity and the development of related conditions, and a new study has shed yet more light on the issue. Scientists have found that modifying so-called “checkpoint proteins” in the immun… Continue reading Tweaks to immune checkpoint proteins apply brakes to obesity→

Targeting “energy crisis” in fat cells could combat effects of obesity

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The interplay between obesity and its many complications, such as type 2 diabetes, is complex and can involve factors such as inflammation and insulin resistance. Better understanding these relationships can reveal new ways to prevent adverse health ef… Continue reading Targeting “energy crisis” in fat cells could combat effects of obesity→

Chemicals in plastics may be a driver of weight gain, study finds

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Obesity rates around the world are on the rise, almost tripling since 1975. While the contribution of things like sugar is well-established, the trend is a complex one involving all manner of lifestyle factors. Scientists at the Norwegian University of… Continue reading Chemicals in plastics may be a driver of weight gain, study finds→

Hydrogel injected into fat stores fights obesity from within

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Next-generation therapies that fight obesity could come in many forms, but one example from Nanyang Technological University that uses a unique combination of light and metabolic function to break down fat has some unique advantages. The team’s solutio… Continue reading Hydrogel injected into fat stores fights obesity from within→

Targeting an enzyme in fat cells drives rapid weight loss in obese mice

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One hormone we are seeing implicated more and more in obesity research goes by the name of leptin, and scientists continue to demonstrate how changing the way the body responds to it might lead to improved health. A new study has shown how targeting an… Continue reading Targeting an enzyme in fat cells drives rapid weight loss in obese mice→

Mitochondria discovery reveals a plant extract that could combat obesity

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Among the many ways obesity negatively impacts the human body is through an impaired metabolism and reduced endurance in skeletal muscle, and a new study has now shed light on a molecular process underpinning the condition. With this new understanding … Continue reading Mitochondria discovery reveals a plant extract that could combat obesity→

Obesity breakthrough safely mimics weight-loss effects of plant compound

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Although it has long been used in traditional Chinese medicine to treat conditions including rheumatoid arthritis and psoriasis, regulatory bodies have warned against the use of celastrol due to the potential for nasty side effects. But the compound ha… Continue reading Obesity breakthrough safely mimics weight-loss effects of plant compound→

Obesity breakthrough reveals how cell “uncoupling” promotes fat burning

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Over the past decade or so, research has shone a light on the different types of fat in the human body, and shown us how some are more desirable than others when it comes to keeping in shape. A new study has revealed a novel signaling pathway through w… Continue reading Obesity breakthrough reveals how cell “uncoupling” promotes fat burning→