Study links Viagra to lower Alzheimer’s risk but experts have reservations

New research proposes Viagra could prevent the development of Alzheimer's disease

A new study published in the journal Nature Aging has identified an association between using Viagra, a popular erectile dysfunction drug, and reduced instances of Alzheimer’s disease. This is not the first time a beneficial link between Viagra and Alzheimer’s has been proposed but clinical trials will be necessary to explore causality.

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Long-term study links amateur boxing to earlier onset of dementia

Researchers found those older men who boxed when they were young were three times more likely to develop Alzheimer's-like cognitive impairments compared to men who did not box

Using data from an ongoing long-term health study spanning 35 years, researchers have found men who participated in amateur boxing in their youth are almost three times more likely to suffer from Alzheimer’s-like cognitive impairment in their senior years compared to those who did not box when young.

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New Alzheimer’s drug leads to brain swelling in one-third of patients

Aducanumab was controversially approved by the FDA in June despite an advisory panel recommending against its approval

A new study published in the journal JAMA Neurology is reporting more than one in three patients trialing the recently approved Alzheimer’s drug aducanumab experienced brain swelling side effects. The data is the first from the controversial drug’s Phase 3 trials to be peer-reviewed and published.

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Quantum brain sensors could enable earlier Alzheimer’s diagnosis

Lead researcher Aikaterini Gialopsou with the instrument where patients' brains are scanned using the new quantum sensors

Researchers at the University of Sussex have demonstrated how an emerging type of quantum sensor could help doctors catch neurodegenerative diseases like Alzheimer’s earlier. The scanners precisely detect tiny changes in magnetic fields produced by firing neurons.

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Discovery of amyloid hairpin structure hints at vaccine for Alzheimer’s

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Though there is so much to learn about the way Alzheimer’s develops in the human brain, amyloid beta proteins have long been implicated in its advance. A new study has uncovered a previously unknown hairpin-like structure within this protein that proved critical to an antibody response seen in mice, with an engineered version of the protein fragment also laying the groundwork for a vaccine against the disease in humans.

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Continue reading Discovery of amyloid hairpin structure hints at vaccine for Alzheimer’s

Discovery of amyloid hairpin structure hints at vaccine for Alzheimer’s

null

Though there is so much to learn about the way Alzheimer’s develops in the human brain, amyloid beta proteins have long been implicated in its advance. A new study has uncovered a previously unknown hairpin-like structure within this protein that proved critical to an antibody response seen in mice, with an engineered version of the protein fragment also laying the groundwork for a vaccine against the disease in humans.

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New evidence shows how viral infections could promote Alzheimer’s

The lab-based research found certain viral molecules could enhance the aggregation of toxic proteins linked with several neurodegenerative diseases

Building on a growing body of evidence linking viral infections with neurodegenerative disease, a new study published in Nature Communications has demonstrated how certain molecules on the surfaces of viruses can promote the aggregation of toxic proteins associated with diseases such as Alzheimer’s and Parkinson’s.

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Viral infections in teenagers linked to later onset of multiple sclerosis

It is hypothesized a severe viral infection in adolescence can trigger a cascade of neuroinflammation leading to the onset of neurological disease years, or even decades, later

A pair of new studies are building on a growing hypothesis that the neurological disease multiple sclerosis (MS) can be triggered by viral infections in a person’s teenage years. The research indicates serious adolescent infections such as glandular fever are associated with higher rates of MS diagnoses, and concerns are being raised as to whether the current COVID-19 pandemic could lead to a surge in MS cases in the future.

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Optimal blood pressure in early adulthood slows the brain’s aging process

Keeping blood pressure to optimal levels might be key to keeping our brains young and healthy, according to new research

The interplay between high blood pressure and brain health is one scientists continue to shed new light on, with studies increasingly linking hypertension to a decline in cognitive function later in life. New research has drilled into the details around when exactly this relationship begins to take shape, finding that it not only begins earlier than suspected, but that even those with blood pressure at the higher end of the normal recommended range can be at risk of premature brain aging.

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Common diuretic pill offers clues to new Alzheimer’s treatment

The research began by looking for existing FDA-approved drugs with the capacity to target genes related to Alzheimer's disease risk

Researchers on the hunt for a pre-approved medicine that can be repurposed to treat Alzheimer’s disease have found promising signs of effectiveness in a 50-year-old generic drug commonly used as a diuretic. Through a variety of animal studies and real-world investigations, the new study indicates exposure to the common drug could significantly reduce a person’s risk of developing Alzheimer’s.

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