OpenLN: Automating Biology for Everyone

When we took a biology lab, you had to use a mouth pipette to transfer liquids around. That always seemed odd to use your mouth to pick up something that could be dangerous. It’s also not very efficient. A modern lab will use a liquid handling robot, but these aren’t exactly cheap. Sometimes these are called pipettors and even a used one on eBay will set you back an average of $1,000 — and many of them much more than that. Now there’s an open source alternative, OpenLH, that can be built for under $1,000 that leverages an open source …read more

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Microfluidics “Frogger” is a Game Changer for DIY Biology

See those blue and green dots in the GIF? Those aren’t pixels on an LCD display. Those are actual drops of liquid moving across a special PCB. The fact that the droplets are being manipulated to play a microfluidics game of “Frogger” only makes OpenDrop v 2.0 even cooler.

Lab biology is mainly an exercise in liquid handling – transferring a little of solution X into some of solution Y with a pipette. Manual pipetting is tedious, error prone, and very low throughput, but automated liquid handling workstations run into the hundreds of thousands of dollars. This makes [Urs Gaudenz]’s …read more

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