Optogenetics for 100 Euros

Larval zebrafish, Drosophila (fruit fly), and Caenorhabditis elegans (roundworm) have become key model organisms in modern neuroscience due to their low maintenance costs and easy sharing of genetic strains across labs. However, the purchase of a commercial solution for experiments using these organisms can be quite costly. Enter FlyPi: a low-cost and modular open-source alternative to commercially available options for optogenetic experimentation.

One of the things that larval zebrafish, fruit flies, and roundworms have in common is that scientists can monitor them individually or in groups in a behavioural arena while controlling the activity of select neurons using optogenetic (light-based) …read more

Continue reading Optogenetics for 100 Euros

Optogenetics for 100 Euros

Larval zebrafish, Drosophila (fruit fly), and Caenorhabditis elegans (roundworm) have become key model organisms in modern neuroscience due to their low maintenance costs and easy sharing of genetic strains across labs. However, the purchase of a commercial solution for experiments using these organisms can be quite costly. Enter FlyPi: a low-cost and modular open-source alternative to commercially available options for optogenetic experimentation.

One of the things that larval zebrafish, fruit flies, and roundworms have in common is that scientists can monitor them individually or in groups in a behavioural arena while controlling the activity of select neurons using optogenetic (light-based) …read more

Continue reading Optogenetics for 100 Euros

The Arduino Sleeps with the Fishes

[Eric Dirgahayu] wanted to explore underwater with some sensors and cameras. First, he needed a platform to carry them. That led to his Arduino-controlled swimming fish. The fish is made from PVC and some waterproof servos. From the video (see below) it isn’t clear how much control the fish has, but it does swim with an undulating motion like a real fish.

The included software allows for infrared control (so clean water is a must) and there is a ballast tank for buoyancy. The site has several videos and tabs that show different aspects of the project. We found the …read more

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Tissue-Engineered Soft Robot Swims Like a Stingray

We’re about to enter a new age in robotics. Forget the servos, the microcontrollers, the H-bridges and the steppers. Start thinking in terms of optogenetically engineered myocytes, microfabricated gold endoskeletons, and hydrodynamically optimized elastomeric skins, because all of these have now come together in a tissue-engineered swimming robotic stingray that pushes the boundary between machine and life.

In a paper in Science, [Kevin Kit Parker] and his team at the fantastically named Wyss Institute for Biologically Inspired Engineering describe the achievement. It turns out that the batoid fishes like skates and rays have a pretty good handle on how …read more

Continue reading Tissue-Engineered Soft Robot Swims Like a Stingray