New study may explain why apathy is the first symptom of Alzheimer’s

New research hypothesizes degeneration in a brain region called the nucleus accumbens could trigger apathy, the earliest psychiatric sign of Alzheimer's disease

Compelling new research from the Indiana University School of Medicine has homed in on a degenerative mechanism that could explain why symptoms such as apathy are the first signs of Alzheimer’s disease. The findings suggest disrupting this process could slow the progression of Alzheimer’s-related dementia.

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Portable MRI can accurately detect most common form of stroke

New research has found the world’s first portable MRI machine can accurately detect ischemic strokes. The machine was cleared for use by the US Food & Drug Administration (FDA) in 2020 and researchers are increasingly demonstrating it to be as effectiv… Continue reading Portable MRI can accurately detect most common form of stroke

Researchers discover direct gut-brain communication pathway

New research published in the journal Science reports the discovery of a unique pathway by which bacteria in the gut can directly communicate with neurons in the brain responsible for regulating appetite and body temperature. The novel mechanism adds t… Continue reading Researchers discover direct gut-brain communication pathway

Chronic e-cigarette use triggers brain, heart & colon inflammation in mice

New research from a team at the University of California San Diego School of Medicine has investigated the effects of chronic pod-based e-cigarette use on inflammation in the brain, heart, lungs and colon. The extensive mouse studies found a variety of… Continue reading Chronic e-cigarette use triggers brain, heart & colon inflammation in mice

MIT surgical robot could let surgeons remotely treat stroke victims

When someone has experienced a stroke or aneurysm, they may require a surgical procedure known as an endovascular intervention. A new MIT-designed robotic system could ensure that they receive the treatment quickly, even if the physician is nowhere nea… Continue reading MIT surgical robot could let surgeons remotely treat stroke victims

New hypothesis argues leaky blood-brain barrier triggers Alzheimer’s

A new hypothesis proposes fatty molecules in the blood stream invade the brain through a leaky blood brain barrier and this processes triggers Alzheimer's disease

A new article in the Journal of Alzheimer’s Disease Reports has proposed a novel hypothesis for the cause of Alzheimer’s disease. The article argues Alzheimer’s is caused by a damaged blood-brain barrier allowing fatty molecules known as lipids to invade the brain and trigger a cascade of events that result in neurodegeneration and cognitive decline.

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World-first massive MRI study charts brain changes from birth to death

More than 100,000 MRI scans were used to develop the first chart measuring normal brain changes over a human lifetime

Hundreds of scientists around the globe have shared data to create the world’s first brain growth chart. The project incorporated MRI scans from subjects of all ages to offer a unique portrait of how our brains change over the course of a lifetime.

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Alzheimer’s-preventing nasal spray targets novel brain mechanism

A nasal spray has been developed to inhibit a brain mechanism hypothesized to be an early driver of Alzheimer's disease

An international team of researchers has reported on the successful preclinical tests of a novel nasal spray developed to prevent neurodegeneration associated with Alzheimer’s disease. The treatment was effective at reversing the pathological signs of Alzheimer’s in mouse models and the researchers are looking to start human tests in two years.

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Landmark study finds 42 new genetic risk factors for Alzheimer’s disease

New research has discovered more than 40 genetic regions previously not associated with Alzheimer's disease risk

A milestone study involving hundreds of scientists from around the world has identified 75 genomic regions associated with Alzheimer’s disease. A number of the newly discovered genetic pathways play a role in inflammation, adding weight to a growing hypothesis immune dysfunction can drive disease progression. Plus, the researchers raise the possibility of developing an Alzheimer’s genetic risk test to predict those most likely to develop the neurodegenerative condition.

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New study shows COVID-19 can cause brain inflammation and small bleeds

A new study published in Nature Communications has offered the most comprehensive investigation to date into the effects of COVID-19 on the brain using nonhuman primates. The study found SARS-CoV-2 infection, regardless of disease severity, can lead to… Continue reading New study shows COVID-19 can cause brain inflammation and small bleeds