Synthesizing Daraprim to Beat Price Gougers
Drugs are used the world over to treat disease. However, from time to time, the vagaries of market economics, or unscrupulous action, can radically increase the price of otherwise cheap pharmaceuticals far beyond the reach of the average person. This was the case with Pyrimethamine (sold as Daraprim), which is used to treat toxoplasmosis and malaria, among other users. With the price skyrocketing from $13 to $750 a tablet in the US in 2015, [NerdRage] decided to synthesize the drug on their own. (If you missed the background hubbub, search for “Martin Shkreli”.)
The video linked covers the final synthesis, …read more
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