RNA-binding proteins discovered to be key to severe asthma

Researchers have investigated the genetics underlying the airway inflammation seen in severe asthma

Researchers investigating the genetics underlying the airway inflammation seen in severe asthma have, for the first time, discovered that proteins that bind to RNA are dysregulated, and drive changes in gene expression in the cells that line the airways.

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Leftovers of cell division spread cancer’s genetic blueprint

Researchers have found that remnants left over after a cell divides contain RNA that, when taken up by other cells, can spread cancer’s genetic blueprint. The finding opens the door to harnessing this mechanism as a way of treating cancer.Continue Read… Continue reading Leftovers of cell division spread cancer’s genetic blueprint

Nobel prize awarded to scientists who set stage for mRNA COVID vaccines

The 2023 Nobel Prize in Physiology or Medicine has been awarded to biochemist Katalin Karikó and immunologist Drew Weissman for discoveries that enabled the development of mRNA vaccines against COVID-19.Continue ReadingCategory: Medical, ScienceTags: N… Continue reading Nobel prize awarded to scientists who set stage for mRNA COVID vaccines

Nobel prize awarded to scientists who set stage for mRNA COVID vaccines

The 2023 Nobel Prize in Physiology or Medicine has been awarded to biochemist Katalin Karikó and immunologist Drew Weissman for discoveries that enabled the development of mRNA vaccines against COVID-19.Continue ReadingCategory: Medical, ScienceTags: N… Continue reading Nobel prize awarded to scientists who set stage for mRNA COVID vaccines

First RNA extracted from extinct species may help thylacine resurrection

Scientists have successfully extracted RNA molecules from an extinct species for the first time. The milestone was achieved in the thylacine, a species of carnivorous marsupial that roamed Australia until about a century ago – and may again one day, if… Continue reading First RNA extracted from extinct species may help thylacine resurrection

Mysterious circular RNA linked to Alzheimer’s & Parkinson’s disease

Researchers have identified a link between circular RNAs and neurodegenerative diseases

Researchers have gained new insights into largely overlooked circular RNAs in brain cells and the crucial role they play in diseases like Alzheimer’s and Parkinson’s. In addition to providing valuable information about the molecular mechanisms underlying these conditions, their findings open the door to developing diagnostic tests and treatments for them.

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Long COVID may be caused by damage to cells’ energy generators

A new study has found that SARS-CoV-2, the virus that causes COVID-19, damages the genes of the mitochondria, the cell’s energy generators, causing dysfunction in organs other than the lungs that continues after the lungs have recovered. The finding ma… Continue reading Long COVID may be caused by damage to cells’ energy generators

RNA therapy targets hard-to-reach bone marrow cancer cells

RNA therapies are emerging as a promising treatment for cancer, but some types of the disease don’t respond well to it. Now, scientists at Tel Aviv University have demonstrated a way to use RNA drugs to treat multiple myeloma, a hard-to-reach cancer th… Continue reading RNA therapy targets hard-to-reach bone marrow cancer cells

Hybrid mRNA and protein vaccine induce 5x more antibodies in mice

Caltech scientists have developed a new type of vaccine that works like a hybrid of mRNA and protein nanoparticles. In tests in mice, the prototype produced five times more antibodies than existing COVID-19 vaccines, and could be put to work against a … Continue reading Hybrid mRNA and protein vaccine induce 5x more antibodies in mice

Open-Source LAMP Instrument Aimed at Clinicians and Biohackers Alike

Over the last few years, we’ve all been given a valuable lesson in both the promise and limitations of advanced molecular biology methods for clinical diagnostics. Polymerase chain reaction (PCR) …read more Continue reading Open-Source LAMP Instrument Aimed at Clinicians and Biohackers Alike